Project Leader:
Dr. Joseph Graziano
Earth Institute Contact: Dr. Joseph Graziano
EI Collaborators:
Steven Chillrud
Annie Gerard
Meredith Golden
Peter Schlosser
Michael Steckler
Martin Stute
Alexander Van Geen
Yan Zheng
Additional External Researchers:
Kazi Matin Ahmed, kmahmed.du.bangla.net;
Habib Ahsan, ha37@columbia.edu (PI);
Conrad Blum, cbb1@worldnet.att.net (PI);
Iftikhar Hussain, iftikhar@bdonline.com;
Mercy Davidson, mmd2@columbia.edu;
Pam Factor-Litvak, prf1@columbia.edu;
Ittai Gavriela, ittai@ldeo.columbia.edu;
Tom Hei, tkh1@columbia.edu (PI);
Geoffrey Howe, gh68@columbia.edu;
Xinhua Liu, liux@nypdrat.cpmc.columbia.edu;
Nancy Lo Iacono, njl2@columbia.edu;
Jack Longley, jl691@columbia.edu;
Lee Marsi, lpm4@columbia.edu;
Xiaoguang Meng, xmeng@stevens-tech.edu;
Nikolaos Nikolaidis, nikos@engr.uconn.edu;
Faruque Parvez, mp844@columbia.edu;
Regina Santella, rps1@columbia.edu;
Vesna Slavkovich, vns1@columbia.edu;
Ponisseril Somasundaran, ps24@columbia.edu (PI);
Wei-Yann Tsai, wt5@columbia.edu;
Roeloff Versteeg, versteeg@ldeo.columbia.edu;
Gail Wasserman, wassermg@child.cpmc.columbia.edu;
Locations: Bangladesh, United States of America
Description:
The primary goal of this program is to obtain new knowledge and to train multi-disciplinary pre- and post-doctoral students regarding the bioavailability of soil lead in humans and the bioavailability, health effects, and geochemistry of arsenic. The proposed work involves studies of bioavailability and/or geochemistry at four Superfund sites in the U.S., two contaminated with lead and two with arsenic. It also encompasses epidemiologic and geochemistry studies of arsenic in drinking water in Bangladesh which focus on carcinogenic, reproductive, and childhood effects of arsenic exposure. We also devote resources to the development of practical remediation strategies for arsenic in wastewater and drinking water.
The program includes four biomedical research projects:
1) Bioavailability of Soil Lead and Arsenic in Humans;
2) Genotoxic Mechanisms of Arsenic in Mammalian Cells;
3) A Cohort Study of Health Effects of Arsenic Exposure in Bangladesh;
4) Environmental Arsenic, Pregnancy, and Children's Health
The biomedical research is directly related to that which occurs in three non-biomedical projects:
5) Arsenic Mobilization in Bangladesh Groundwater;
6) Redistribution of Arsenic at Sites in New Jersey and Maine; and
7) Assessment and Remediation for Arsenic Enrichments in Groundwater.
The projects are supported by three Research Support Core Labs:
8) Trace Metals;
9) Geochemistry; and
10) Hydrogeology
An Administrative Core includes an Information Dissemination Program and a Government Liaison & Outreach Program. Finally, a Training Core coordinates multi-disciplinary education and interaction among pre- and post-doctoral trainees supported by this grant as well as other training grants.
EI Unit:
Center for Global Health and Economic Development (CGHED)
Cross Cutting Themes:
Hazards and Risk
Core Disciplines:
Health
Project Web Site:
http://superfund.ciesin.columbia.edu/home.html
Collaborating Institutions:
Mailman School of Public Health, Department of Epidemiology
(http://cpmcnet.columbia.edu/dept/sph/epi/index.html)
Lamont-Doherty Earth Observatory
(http://www.ldeo.columbia.edu/)
Center for International Earth Sciences Information Network-CIESIN
(www.ciesin.columbia.edu)
Henry Krumb School of Mines
(http://www.columbia.edu/cu/gsas/depts/chmm.html)
Columbia University College of Physicians & Surgeons
(http://cpmcnet.columbia.edu/dept/ps/)
School of International & Public Affairs
(http://www.sipa.columbia.edu/)
University of Connecticut
Stevens Institute of Technology
Queens College, NY
National Institute of Preventive and Social Medicine (NIPSOM), Dhaka, Bangladesh
Department of Geology, Dhaka University, Bangladesh
Funding Agency:
NIEHS
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